Targeted mutagenesis of the farnesylation site of Drosophila Ggammae disrupts membrane association of the G protein betagamma complex and affects the light sensitivity of the visual system. [electronic resource]
Producer: 20041006Description: 36309-16 p. digitalISSN:- 0021-9258
- Amino Acid Motifs
- Animals
- Animals, Genetically Modified
- Blotting, Western
- Cell Membrane -- metabolism
- Crystallins -- genetics
- Cysteine -- chemistry
- DNA -- metabolism
- Drosophila
- Electrophoresis, Polyacrylamide Gel
- Electroretinography
- Heterotrimeric GTP-Binding Proteins -- physiology
- Immunohistochemistry
- Isoenzymes -- metabolism
- Light
- Mass Spectrometry
- Models, Chemical
- Mutagenesis, Site-Directed
- Mutation
- Phospholipase C beta
- Photophobia
- Photoreceptor Cells, Invertebrate -- metabolism
- Point Mutation
- Precipitin Tests
- Protein Prenylation
- Protein Processing, Post-Translational
- Retina -- metabolism
- Rhodopsin -- chemistry
- Transgenes
- Type C Phospholipases -- metabolism
- gamma-Crystallins
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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