Evidence for a dominant-negative effect in ACTA1 nemaline myopathy caused by abnormal folding, aggregation and altered polymerization of mutant actin isoforms. [electronic resource]
Producer: 20050225Description: 1727-43 p. digitalISSN:- 0964-6906
- Actins -- genetics
- Biopolymers -- genetics
- Blotting, Western
- Cells, Cultured
- DNA Primers
- Histological Techniques
- Humans
- Immunoblotting
- Immunohistochemistry
- Isoelectric Focusing
- Models, Molecular
- Muscle Proteins -- metabolism
- Mutation -- genetics
- Myoblasts -- metabolism
- Myopathies, Nemaline -- genetics
- Protein Folding
- Protein Isoforms -- genetics
- Transfection
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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