Puromycin-insensitive leucyl-specific aminopeptidase (PILSAP) binds and catalyzes PDK1, allowing VEGF-stimulated activation of S6K for endothelial cell proliferation and angiogenesis. [electronic resource]
Producer: 20041123Description: 2345-52 p. digitalISSN:- 0006-4971
- 3-Phosphoinositide-Dependent Protein Kinases
- Animals
- Catalysis -- drug effects
- Cell Cycle
- Cell Division
- Cell Line
- Cyclin-Dependent Kinases -- metabolism
- DNA -- biosynthesis
- Endothelial Cells -- cytology
- Enzyme Activation -- drug effects
- Humans
- Leucyl Aminopeptidase -- genetics
- Male
- Mice
- Mutation -- genetics
- Neoplasms -- blood supply
- Neovascularization, Pathologic
- Phosphorylation
- Protein Binding
- Protein Serine-Threonine Kinases -- metabolism
- Retinoblastoma Protein -- metabolism
- Ribosomal Protein S6 Kinases -- metabolism
- Vascular Endothelial Growth Factor A -- pharmacology
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.