Identification of a compensatory mutant (lpg2-REV) of Leishmania major able to survive as amastigotes within macrophages without LPG2-dependent glycoconjugates and its significance to virulence and immunization strategies. [electronic resource]
Producer: 20040623Description: 3622-7 p. digitalISSN:- 0019-9567
- Animals
- Female
- Glycoconjugates -- metabolism
- Glycosphingolipids -- genetics
- Humans
- Immunization
- Leishmania major -- genetics
- Leishmaniasis, Cutaneous -- parasitology
- Macrophages, Peritoneal -- parasitology
- Membrane Proteins -- genetics
- Mice
- Mice, Inbred BALB C
- Mutation
- Protozoan Proteins -- genetics
- Protozoan Vaccines
- Virulence
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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