Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region. [electronic resource]
Producer: 20040910Description: 32592-602 p. digitalISSN:- 0021-9258
- Amino Acid Motifs
- Amino Acid Sequence
- Binding Sites
- Blotting, Western
- CDC2 Protein Kinase -- metabolism
- Carcinoma, Hepatocellular -- metabolism
- Cell Cycle
- Cell Line
- Cyclin B -- metabolism
- Cycloheximide -- pharmacology
- DNA, Complementary -- metabolism
- Databases as Topic
- Electrophoresis, Polyacrylamide Gel
- Enzyme Inhibitors -- pharmacology
- F-Box Proteins -- metabolism
- Genetic Vectors
- Humans
- Microscopy, Fluorescence
- Mitosis
- Models, Biological
- Models, Genetic
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Neoplasm Proteins -- metabolism
- Nocodazole -- pharmacology
- Phosphoproteins -- chemistry
- Phosphorylation
- Precipitin Tests
- Proline -- chemistry
- Protein Binding
- Protein Biosynthesis
- Protein Structure, Tertiary
- Protein Synthesis Inhibitors -- pharmacology
- RNA, Small Interfering -- metabolism
- Recombinant Proteins -- chemistry
- Recombination, Genetic
- Sequence Homology, Amino Acid
- Stem Cell Factor -- metabolism
- Substrate Specificity
- Temperature
- Time Factors
- Transfection
- Ubiquitin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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