In pneumococcal meningitis a novel water-soluble inhibitor of matrix metalloproteinases and TNF-alpha converting enzyme attenuates seizures and injury of the cerebral cortex. [electronic resource]
Producer: 20040818Description: 6-11 p. digitalISSN:- 0165-5728
- ADAM Proteins
- ADAM17 Protein
- Animals
- Animals, Newborn
- Apoptosis -- drug effects
- Cerebral Cortex -- drug effects
- Disease Models, Animal
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Enzyme-Linked Immunosorbent Assay
- Matrix Metalloproteinase Inhibitors
- Matrix Metalloproteinases -- drug effects
- Meningitis, Pneumococcal -- complications
- Metalloendopeptidases -- antagonists & inhibitors
- Rats
- Rats, Sprague-Dawley
- Seizures -- drug therapy
- Tumor Necrosis Factor-alpha -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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