Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125. [electronic resource]
Producer: 20050616Description: 2185-95 p. digitalISSN:- 0261-4189
- Adaptor Proteins, Signal Transducing -- chemistry
- Adenosine Triphosphate -- metabolism
- Allosteric Regulation
- Anthracenes -- metabolism
- Arginine -- chemistry
- Binding Sites
- Blotting, Western
- Calorimetry
- Crystallography, X-Ray
- Glutamic Acid -- chemistry
- HeLa Cells
- Humans
- Hydrogen Bonding
- Leucine -- chemistry
- Mitogen-Activated Protein Kinase 8 -- antagonists & inhibitors
- Models, Molecular
- Proline -- chemistry
- Protein Binding
- Protein Conformation
- Protein Structure, Tertiary
- Signal Transduction
- Transfection
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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