ERK activation and subsequent RB phosphorylation are important determinants of the sensitivity to paclitaxel in lung adenocarcinoma cells. [electronic resource]
Producer: 20041228Description: 1499-504 p. digitalISSN:- 1019-6439
- Adenocarcinoma -- drug therapy
- Antineoplastic Agents, Phytogenic -- pharmacology
- Drug Resistance, Neoplasm
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- G1 Phase -- drug effects
- Gene Expression Regulation, Neoplastic
- Humans
- Lung Neoplasms -- drug therapy
- Paclitaxel -- pharmacology
- Phosphorylation -- drug effects
- Retinoblastoma Protein -- drug effects
- Tumor Cells, Cultured
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Publication Type: Comparative Study; Journal Article
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