BRD7, a novel bromodomain gene, inhibits G1-S progression by transcriptionally regulating some important molecules involved in ras/MEK/ERK and Rb/E2F pathways. [electronic resource]
Producer: 20040702Description: 89-98 p. digitalISSN:- 0021-9541
- Blotting, Western
- Carcinoma -- genetics
- Carrier Proteins -- genetics
- Cell Cycle Proteins
- Cell Line, Tumor
- Chromosomal Proteins, Non-Histone -- genetics
- Colony-Forming Units Assay
- DNA-Binding Proteins -- genetics
- E2F Transcription Factors
- E2F3 Transcription Factor
- Flow Cytometry
- G1 Phase
- Gene Expression Regulation, Neoplastic
- Genes, Reporter
- Genes, ras
- Humans
- Luciferases -- metabolism
- Mitogen-Activated Protein Kinases -- genetics
- Models, Biological
- Nasopharyngeal Neoplasms -- genetics
- Nuclear Proteins -- genetics
- Oligonucleotide Array Sequence Analysis
- Promoter Regions, Genetic
- Retinoblastoma Protein -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- S Phase
- Transcription Factors -- genetics
- Transcription, Genetic
- ras Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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