Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis. [electronic resource]
Producer: 20040629Description: 4681-9 p. digitalISSN:- 0950-9232
- Animals
- Blotting, Western
- Cathepsin B -- administration & dosage
- Cell Division -- genetics
- Cell Line, Tumor
- Cell Movement -- genetics
- Collagen -- metabolism
- Down-Regulation
- Drug Combinations
- Gene Expression Regulation, Neoplastic
- Glioblastoma -- blood supply
- Humans
- Injections, Intraperitoneal
- Injections, Intraventricular
- Laminin -- metabolism
- Matrix Metalloproteinase 9 -- administration & dosage
- Mice
- Mice, Nude
- Models, Biological
- Neoplasm Invasiveness
- Neoplasm Transplantation
- Neovascularization, Pathologic -- genetics
- Proteoglycans -- metabolism
- RNA Interference
- Spheroids, Cellular
- Transplantation, Heterologous
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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