Transfection of RNA encoding tumor antigens following maturation of dendritic cells leads to prolonged presentation of antigen and the generation of high-affinity tumor-reactive cytotoxic T lymphocytes. [electronic resource]
Producer: 20041217Description: 757-64 p. digitalISSN:- 1525-0016
- Antigens, Neoplasm -- genetics
- Cell Line
- Dendritic Cells -- immunology
- Epitopes -- genetics
- Humans
- Lymphocyte Activation
- MART-1 Antigen
- Neoplasm Proteins -- genetics
- Neoplasms -- immunology
- RNA, Neoplasm -- genetics
- T-Lymphocytes, Cytotoxic -- immunology
- Transfection -- methods
- Vaccination -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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