Synthetic selective inhibitors of coagulation factor Xa strongly inhibit thrombin generation without affecting initial thrombin forming time necessary for platelet activation in hemostasis. [electronic resource]
Producer: 20041019Description: 612-8 p. digitalISSN:- 1538-7933
- Anticoagulants -- chemistry
- Arginine -- analogs & derivatives
- Blood Platelets
- Cells, Cultured
- Enzyme Inhibitors -- pharmacology
- Factor Xa Inhibitors
- Hemostasis -- drug effects
- Humans
- Naphthalenes -- pharmacology
- Partial Thromboplastin Time
- Pipecolic Acids -- pharmacology
- Piperidines -- pharmacology
- Platelet Activation -- drug effects
- Propionates -- pharmacology
- Prothrombin Time
- Pyridines -- pharmacology
- Sulfonamides
- Tetrahydroisoquinolines -- pharmacology
- Thrombin -- biosynthesis
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Publication Type: Journal Article
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