CNTO 95, a fully human monoclonal antibody that inhibits alphav integrins, has antitumor and antiangiogenic activity in vivo. [electronic resource]
Producer: 20040614Description: 326-35 p. digitalISSN:- 0020-7136
- Animals
- Antibodies, Monoclonal -- chemistry
- Antibodies, Monoclonal, Humanized
- Antibody Affinity
- Antibody Specificity
- Antineoplastic Agents -- pharmacology
- Aorta -- metabolism
- Blotting, Western
- Cattle
- Cell Adhesion
- Cell Division
- Cell Line
- Cell Line, Tumor
- Cell Movement
- Cells, Cultured
- Collagen -- pharmacology
- Dose-Response Relationship, Drug
- Drug Combinations
- Endothelium, Vascular -- cytology
- Fibroblast Growth Factor 2 -- metabolism
- Haplorhini
- Humans
- Integrin alphaV -- chemistry
- Integrin alphaVbeta3 -- metabolism
- Integrins -- metabolism
- Kinetics
- Laminin -- pharmacology
- Macaca fascicularis
- Melanoma -- immunology
- Mice
- Mice, Nude
- Neoplasm Invasiveness
- Neoplasm Transplantation
- Neovascularization, Pathologic
- Placenta -- metabolism
- Protein Binding
- Proteoglycans -- pharmacology
- Rats
- Rats, Nude
- Receptors, Vitronectin -- metabolism
- Time Factors
No physical items for this record
Publication Type: Journal Article
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