TNF-alpha-mediated lysosomal permeabilization is FAN and caspase 8/Bid dependent. [electronic resource]
Producer: 20040830Description: G436-43 p. digitalISSN:- 0193-1857
- Adaptor Proteins, Signal Transducing
- Animals
- Apoptosis -- physiology
- BH3 Interacting Domain Death Agonist Protein
- Carrier Proteins -- genetics
- Caspase 8
- Caspases -- metabolism
- Cathepsin B -- metabolism
- Cells, Cultured
- Dactinomycin -- pharmacology
- Enzyme Activation -- drug effects
- Fas-Associated Death Domain Protein
- Green Fluorescent Proteins
- Intracellular Signaling Peptides and Proteins
- Luminescent Proteins -- genetics
- Lysosomes -- metabolism
- Mice
- Mice, Knockout
- Permeability -- drug effects
- Proteins -- physiology
- Rats
- Recombinant Fusion Proteins -- pharmacology
- Tumor Necrosis Factor-alpha -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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