Adenovirus-mediated interleukin-18 mutant in vivo gene transfer inhibits tumor growth through the induction of T cell immunity and activation of natural killer cell cytotoxicity. [electronic resource]
Producer: 20041216Description: 397-407 p. digitalISSN:- 0929-1903
- Adenoviridae -- genetics
- Animals
- CD4-Positive T-Lymphocytes -- metabolism
- CD8-Positive T-Lymphocytes -- metabolism
- Cell Line
- Cell Line, Tumor
- Cloning, Molecular
- Culture Media -- pharmacology
- DNA, Complementary -- metabolism
- Enzyme-Linked Immunosorbent Assay
- Female
- Gene Transfer Techniques
- Granulocyte-Macrophage Colony-Stimulating Factor -- metabolism
- Green Fluorescent Proteins -- metabolism
- Humans
- Immunohistochemistry
- Immunoprecipitation
- Interferon-gamma -- metabolism
- Interleukin-18 -- genetics
- Interleukin-2 -- metabolism
- Kidney Neoplasms -- therapy
- Killer Cells, Natural -- metabolism
- Liver Neoplasms -- therapy
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Models, Genetic
- Mutation
- T-Lymphocytes -- cytology
- Time Factors
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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