Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist. [electronic resource]
Producer: 20040916Description: 805-14 p. digitalISSN:- 0022-1007
- Adaptor Proteins, Signal Transducing
- Alkaline Phosphatase -- metabolism
- Animals
- Bone Development -- physiology
- Bone Diseases, Developmental -- metabolism
- Bone Morphogenetic Proteins -- genetics
- Cells, Cultured
- DNA Primers
- DNA, Complementary -- genetics
- DNA-Binding Proteins -- metabolism
- Disease Models, Animal
- Gene Expression Regulation, Developmental
- Genetic Markers -- genetics
- Glycoproteins
- Homeodomain Proteins
- Humans
- Immunohistochemistry
- In Situ Hybridization
- Intercellular Signaling Peptides and Proteins
- Luciferases
- Mice
- Osteoblasts -- metabolism
- Phosphorylation
- Reverse Transcriptase Polymerase Chain Reaction
- Smad Proteins
- Trans-Activators -- metabolism
- Transfection
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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