Targeted prevention of renal accumulation and toxicity of gentamicin by aminoglycoside binding receptor antagonists. [electronic resource]
Producer: 20050114Description: 423-33 p. digitalISSN:- 0168-3659
- Acetylglucosaminidase -- antagonists & inhibitors
- Aminoglycosides -- administration & dosage
- Animals
- Aprotinin -- pharmacology
- Binding Sites -- drug effects
- Cells, Cultured
- Cytochromes c -- chemistry
- Dehydration -- drug therapy
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Delivery Systems -- methods
- Drug Evaluation, Preclinical -- methods
- Drug Therapy, Combination
- Endocytosis -- drug effects
- Gentamicins -- adverse effects
- Japan
- Kidney Cortex -- drug effects
- Kidney Tubules, Proximal -- cytology
- Low Density Lipoprotein Receptor-Related Protein-2 -- administration & dosage
- Male
- Mice
- Mice, Inbred Strains
- Muramidase -- pharmacology
- Nerve Tissue Proteins -- chemistry
- Peptide Fragments -- chemical synthesis
- Peptides -- chemical synthesis
- Rats
- Rats, Wistar
- Receptors, Drug -- antagonists & inhibitors
- Species Specificity
- Tissue Distribution -- drug effects
- Tritium
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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