Structure of an allosteric inhibitor of LFA-1 bound to the I-domain studied by crystallography, NMR, and calorimetry. [electronic resource]
Producer: 20040629Description: 2394-404 p. digitalISSN:- 0006-2960
- Allosteric Site
- Amides -- chemistry
- Binding, Competitive
- Calorimetry
- Cinnamates -- chemistry
- Crystallography, X-Ray
- Drug Design
- Humans
- Ligands
- Lymphocyte Function-Associated Antigen-1 -- chemistry
- Models, Molecular
- Nuclear Magnetic Resonance, Biomolecular
- Protein Binding
- Protein Structure, Tertiary
- Protein Subunits -- antagonists & inhibitors
- Recombinant Proteins -- antagonists & inhibitors
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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