In psoriasis lesional skin the type I interferon signaling pathway is activated, whereas interferon-alpha sensitivity is unaltered. [electronic resource]
Producer: 20040304Description: 51-60 p. digitalISSN:- 0022-202X
- Adolescent
- Adult
- Aged
- Antineoplastic Agents -- metabolism
- Biopsy
- Cell Nucleus -- metabolism
- Cells, Cultured
- DNA-Binding Proteins -- genetics
- Female
- Gene Expression -- immunology
- Humans
- Interferon Regulatory Factor-7
- Interferon-Stimulated Gene Factor 3
- Interferon-Stimulated Gene Factor 3, gamma Subunit
- Interferon-alpha -- metabolism
- Interferon-beta -- metabolism
- Keratinocytes -- cytology
- Male
- Middle Aged
- Phenotype
- Psoriasis -- metabolism
- RNA, Messenger -- analysis
- STAT1 Transcription Factor
- Signal Transduction -- drug effects
- Trans-Activators -- metabolism
- Transcription Factors -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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