The Pro-451 to Leu polymorphism within the C-terminal tail of P2X7 receptor impairs cell death but not phospholipase D activation in murine thymocytes. [electronic resource]
Producer: 20040610Description: 16918-26 p. digitalISSN:- 0021-9258
- Adenosine Triphosphate -- analogs & derivatives
- Animals
- Annexin A5 -- pharmacology
- Cell Membrane -- metabolism
- DNA Fragmentation
- Dose-Response Relationship, Drug
- Enzyme Activation
- Flow Cytometry
- In Situ Nick-End Labeling
- L-Lactate Dehydrogenase -- metabolism
- Leucine -- chemistry
- Ligands
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Transgenic
- Mutation
- Phospholipase D -- metabolism
- Platelet Aggregation Inhibitors -- pharmacology
- Polymorphism, Genetic
- Proline -- chemistry
- Protein Structure, Tertiary
- Pyridoxal Phosphate -- analogs & derivatives
- Receptors, Purinergic P2 -- chemistry
- Receptors, Purinergic P2X7
- Thymoma -- pathology
- Thymus Gland -- cytology
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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