Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death. [electronic resource]
Producer: 20040923Description: 53-64 p. digitalISSN:- 0891-5849
- Animals
- Apoptosis -- drug effects
- Cells, Cultured
- Cellular Senescence -- drug effects
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins -- genetics
- DNA -- biosynthesis
- Electrophoretic Mobility Shift Assay
- Female
- Fibroblasts
- Gene Deletion
- Glutathione Peroxidase -- deficiency
- Hydrogen Peroxide -- pharmacology
- Male
- Mice
- Mice, Knockout
- RNA, Messenger -- genetics
- Glutathione Peroxidase GPX1
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Publication Type: Journal Article
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