Induction of survivin expression by taxol (paclitaxel) is an early event, which is independent of taxol-mediated G2/M arrest. [electronic resource]
Producer: 20040601Description: 15196-203 p. digitalISSN:- 0021-9258
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis
- Base Sequence
- Blotting, Western
- Cell Death
- Cell Line, Tumor
- Cell Survival
- Coloring Agents -- pharmacology
- Cyclin B -- metabolism
- Cyclin B1
- DNA -- chemistry
- Dose-Response Relationship, Drug
- Flow Cytometry
- G2 Phase
- Humans
- Inhibitor of Apoptosis Proteins
- Luciferases -- metabolism
- MAP Kinase Kinase Kinase 1
- MAP Kinase Kinase Kinases -- metabolism
- Microscopy, Fluorescence
- Microtubule-Associated Proteins -- biosynthesis
- Mitosis
- Molecular Sequence Data
- Neoplasm Proteins
- Paclitaxel -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation
- Propidium -- pharmacology
- RNA, Small Interfering -- metabolism
- Survivin
- Time Factors
- Transfection
- Trypan Blue -- pharmacology
- Up-Regulation
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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