Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation. [electronic resource]
Producer: 20040308Description: 227-35 p. digitalISSN:- 0014-5793
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid -- metabolism
- Adenosine Diphosphate -- analogs & derivatives
- Adenosine Monophosphate -- analogs & derivatives
- Animals
- Cattle
- Collagen -- metabolism
- Enzyme Activation -- drug effects
- Epinephrine -- pharmacology
- GTP-Binding Protein alpha Subunits, Gi-Go -- metabolism
- Humans
- Integrin alpha2beta1 -- metabolism
- Membrane Proteins -- antagonists & inhibitors
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Phosphorylation
- Platelet Aggregation -- drug effects
- Platelet Membrane Glycoproteins -- metabolism
- Protein Kinase C -- metabolism
- Purinergic P2 Receptor Antagonists
- Receptors, Purinergic P2 -- metabolism
- Receptors, Purinergic P2Y12
- Receptors, Thromboxane A2, Prostaglandin H2 -- antagonists & inhibitors
- Signal Transduction
- Thromboxane A2 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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