The bisphosphonate zoledronic acid induces cytotoxicity in human myeloma cell lines with enhancing effects of dexamethasone and thalidomide. [electronic resource]
Producer: 20040427Description: 443-9 p. digitalISSN:- 0925-5710
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Calcium -- metabolism
- Cell Cycle -- drug effects
- Cell Division -- drug effects
- Dexamethasone -- pharmacology
- Diphosphonates -- pharmacology
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Drug Synergism
- Egtazic Acid -- pharmacology
- Enzyme Inhibitors -- pharmacology
- Humans
- Imidazoles -- pharmacology
- Leukemia, Plasma Cell -- pathology
- Multiple Myeloma -- pathology
- NG-Nitroarginine Methyl Ester -- pharmacology
- Neoplasm Proteins -- antagonists & inhibitors
- Nitric Oxide Synthase -- antagonists & inhibitors
- Protein Kinase C -- antagonists & inhibitors
- Staurosporine -- pharmacology
- Thalidomide -- pharmacology
- Tumor Cells, Cultured -- drug effects
- Zoledronic Acid
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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