Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents. [electronic resource]
Producer: 20040224Description: 143-57 p. digitalISSN:- 0022-2623
- Animals
- Antipsychotic Agents -- chemical synthesis
- Avoidance Learning -- drug effects
- Benzothiepins -- chemical synthesis
- Catalepsy -- chemically induced
- Cognition Disorders -- chemically induced
- Dopamine Antagonists -- chemical synthesis
- Humans
- Male
- Mice
- Models, Molecular
- Motor Activity -- drug effects
- Pituitary Gland, Anterior -- drug effects
- Prolactin -- metabolism
- Pyrroles -- chemical synthesis
- Rats
- Rats, Inbred F344
- Rats, Wistar
- Receptors, Dopamine D1 -- metabolism
- Receptors, Dopamine D2 -- metabolism
- Receptors, Dopamine D3
- Receptors, Serotonin, 5-HT2 -- metabolism
- Serotonin Antagonists -- chemical synthesis
- Structure-Activity Relationship
- Thiazepines -- chemical synthesis
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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