The 2G single nucleotide polymorphism (SNP) in the MMP-1 promoter contributes to high levels of MMP-1 transcription in MCF-7/ADR breast cancer cells. [electronic resource]
Producer: 20040408Description: 75-82 p. digitalISSN:- 0167-6806
- Binding Sites -- genetics
- Breast Neoplasms -- genetics
- Cell Line, Tumor -- drug effects
- Collagen Type I -- metabolism
- Down-Regulation
- Enzyme Inhibitors -- pharmacology
- Flavonoids -- pharmacology
- Gene Expression Regulation, Enzymologic -- drug effects
- Humans
- Imidazoles -- pharmacology
- In Vitro Techniques
- Matrix Metalloproteinase 1 -- genetics
- Mitogen-Activated Protein Kinase 1 -- antagonists & inhibitors
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic -- genetics
- Pyridines -- pharmacology
- RNA, Messenger -- genetics
- Transcription Factor AP-1 -- metabolism
- Transcription, Genetic
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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