Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth. [electronic resource]
Producer: 20060113Description: E83 p. digitalISSN:- 1545-7885
- Adenocarcinoma, Clear Cell -- genetics
- Alleles
- Animals
- Base Sequence
- Basic Helix-Loop-Helix Transcription Factors -- antagonists & inhibitors
- Binding Sites
- Cell Line, Tumor
- Cell Proliferation
- Dimerization
- Down-Regulation
- Gene Expression Regulation, Neoplastic
- Gene Silencing
- Genetic Variation
- Humans
- Immunoblotting
- Kidney Neoplasms -- genetics
- Mice
- Mice, Nude
- Molecular Sequence Data
- Neoplasm Transplantation
- Oxygen -- metabolism
- Plasmids -- metabolism
- Protein Binding
- Protein Structure, Tertiary
- RNA -- chemistry
- RNA, Small Interfering -- metabolism
- Retroviridae -- genetics
- Von Hippel-Lindau Tumor Suppressor Protein -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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