A nitric oxide (NO)-releasing derivative of gabapentin, NCX 8001, alleviates neuropathic pain-like behavior after spinal cord and peripheral nerve injury. [electronic resource]
Producer: 20050124Description: 65-74 p. digitalISSN:- 0007-1188
- Acetates -- chemistry
- Amines -- metabolism
- Animals
- Aorta, Thoracic -- cytology
- Behavior, Animal -- drug effects
- Cyclic GMP -- biosynthesis
- Cyclohexanecarboxylic Acids -- metabolism
- Cyclohexanes -- chemistry
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Evaluation, Preclinical
- Female
- Gabapentin
- Humans
- Injections, Intraperitoneal
- Lipopolysaccharides -- adverse effects
- Macrophages -- drug effects
- Male
- Mice
- Muscle, Smooth -- drug effects
- Nitrates -- metabolism
- Nitric Oxide -- metabolism
- PC12 Cells
- Pain -- complications
- Pain Measurement -- methods
- Peripheral Nerve Injuries
- Peripheral Nerves -- drug effects
- Rabbits
- Randomized Controlled Trials as Topic
- Rats
- Rats, Sprague-Dawley
- Sciatic Neuropathy -- drug therapy
- Spinal Cord Injuries -- drug therapy
- Tumor Necrosis Factor-alpha -- metabolism
- Vasodilation -- drug effects
- gamma-Aminobutyric Acid -- metabolism
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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