Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms. [electronic resource]
Producer: 20040224Description: 338-40 p. digitalISSN:- 1530-6860
- Animals
- Apoptosis
- Cell Survival -- drug effects
- Hypoxia
- Indoles -- pharmacology
- Microcirculation -- drug effects
- Models, Biological
- Neoplasms -- blood supply
- Neovascularization, Pathologic -- drug therapy
- Oxindoles
- Pericytes -- cytology
- Platelet-Derived Growth Factor -- antagonists & inhibitors
- Propionates
- Pyrroles -- pharmacology
- Receptor, Platelet-Derived Growth Factor beta -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Vascular Endothelial Growth Factor A -- antagonists & inhibitors
- Vascular Endothelial Growth Factor Receptor-2 -- antagonists & inhibitors
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Publication Type: Journal Article
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