Potent ligand-independent estrogen receptor activation by 3,3'-diindolylmethane is mediated by cross talk between the protein kinase A and mitogen-activated protein kinase signaling pathways. [electronic resource]
Producer: 20041202Description: 291-302 p. digitalISSN:- 0888-8809
- Adenocarcinoma -- drug therapy
- Anticarcinogenic Agents -- pharmacology
- Cyclic AMP Response Element-Binding Protein
- Cyclic AMP-Dependent Protein Kinases -- antagonists & inhibitors
- Cycloheximide -- pharmacology
- Endometrial Neoplasms -- drug therapy
- Enzyme Inhibitors -- pharmacology
- Estradiol -- analogs & derivatives
- Estrogen Antagonists -- pharmacology
- Estrogen Receptor alpha -- drug effects
- Female
- Flavonoids -- pharmacology
- Fulvestrant
- Humans
- Indoles -- pharmacology
- Isoquinolines -- pharmacology
- Ligands
- MAP Kinase Signaling System -- drug effects
- Phosphoprotein Phosphatases -- antagonists & inhibitors
- Phosphorylation -- drug effects
- Point Mutation
- Sulfonamides -- pharmacology
- Transcription Factors -- drug effects
- Transcriptional Activation
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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