Systemic administration of IL-18 promotes diabetes development in young nonobese diabetic mice. [electronic resource]
Producer: 20040301Description: 5865-75 p. digitalISSN:- 0022-1767
- Age Factors
- Animals
- Antigens, CD -- biosynthesis
- B7-2 Antigen
- Chemokine CXCL10
- Chemokines, CXC -- biosynthesis
- Cytokines -- biosynthesis
- Diabetes Mellitus, Type 1 -- epidemiology
- Female
- Genetic Vectors
- Glutamate Decarboxylase -- metabolism
- Incidence
- Injections, Intramuscular
- Interferon-gamma -- biosynthesis
- Interleukin-12 -- biosynthesis
- Interleukin-12 Subunit p40
- Interleukin-18 -- administration & dosage
- Islets of Langerhans -- immunology
- Lymphocyte Count
- Membrane Glycoproteins -- biosynthesis
- Mice
- Mice, Inbred NOD
- Pancreas -- immunology
- Plasmids
- Protein Subunits -- biosynthesis
- RNA, Messenger -- analysis
- Reverse Transcriptase Polymerase Chain Reaction
- Severity of Illness Index
- Th1 Cells -- enzymology
- Up-Regulation -- immunology
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Publication Type: Journal Article
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