PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase. [electronic resource]
Producer: 20031219Description: 8460-71 p. digitalISSN:- 0950-9232
- Animals
- Binding Sites
- Cell Cycle Proteins
- Cyclin A -- metabolism
- DNA-Binding Proteins
- E2F Transcription Factors
- E2F1 Transcription Factor
- Genes, myc -- physiology
- Humans
- Poly(ADP-ribose) Polymerases -- metabolism
- Precipitin Tests
- S Phase -- physiology
- Transcription Factors -- metabolism
- Transcription, Genetic
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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