Reduced c-Met expression by an adenovirus expressing a c-Met ribozyme inhibits tumorigenic growth and lymph node metastases of PC3-LN4 prostate tumor cells in an orthotopic nude mouse model. [electronic resource]
Producer: 20040719Description: 5161-70 p. digitalISSN:- 1078-0432
- Adenoviruses, Human -- genetics
- Animals
- Cell Movement
- Disease Models, Animal
- Down-Regulation
- Genetic Therapy
- Humans
- Lymphatic Metastasis -- prevention & control
- Male
- Mice
- Mice, Nude
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinases -- metabolism
- Neoplasm Invasiveness
- Prostatic Neoplasms -- genetics
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- Proto-Oncogene Proteins c-met -- genetics
- RNA, Catalytic -- genetics
- Transfection
- Tumor Cells, Cultured
- Vascular Endothelial Growth Factor A -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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