Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA. [electronic resource]
Producer: 20040116Description: 7291-300 p. digitalISSN:- 0008-5472
- Acetylation -- drug effects
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- DNA Topoisomerases, Type II -- metabolism
- DNA, Neoplasm -- drug effects
- Drug Synergism
- Enzyme Inhibitors -- pharmacology
- Etoposide -- pharmacology
- Gene Expression -- drug effects
- Glioblastoma -- drug therapy
- Histone Deacetylase Inhibitors
- Humans
- Hydroxamic Acids -- pharmacology
- Tumor Suppressor Protein p53 -- physiology
- Vorinostat
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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