Effect of rifampicin on the pharmacokinetics of imatinib mesylate (Gleevec, STI571) in healthy subjects. [electronic resource]
Producer: 20040309Description: 102-6 p. digitalISSN:- 0344-5704
- Adult
- Antibiotics, Antitubercular -- adverse effects
- Antineoplastic Agents -- adverse effects
- Area Under Curve
- Aryl Hydrocarbon Hydroxylases -- biosynthesis
- Benzamides
- Biotransformation
- Cytochrome P-450 CYP3A
- Drug Interactions
- Enzyme Induction -- drug effects
- Female
- Half-Life
- Humans
- Hydrocortisone -- blood
- Imatinib Mesylate
- Male
- Oxidoreductases, N-Demethylating -- biosynthesis
- Piperazines -- adverse effects
- Pyrimidines -- adverse effects
- Rifampin -- adverse effects
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Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
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