Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity. [electronic resource]
Producer: 20040615Description: 517-27 p. digitalISSN:- 1523-0864
- Acyltransferases -- analysis
- Administration, Oral
- Age Factors
- Aging -- physiology
- Aldehydes -- chemistry
- Amino Acid Sequence
- Animals
- Blotting, Western
- Catalysis
- Creatine Kinase -- analysis
- Cross-Linking Reagents -- chemistry
- Dihydrolipoamide Dehydrogenase -- analysis
- Electrophoresis, Polyacrylamide Gel
- Enzyme Inhibitors -- chemistry
- Gene Expression
- Ketoglutarate Dehydrogenase Complex -- chemistry
- Kinetics
- Male
- Mitochondria, Heart -- chemistry
- Molecular Sequence Data
- Myocardium -- chemistry
- Rats
- Rats, Inbred F344
- Serum Albumin -- analysis
- Spectrometry, Mass, Electrospray Ionization
- Swine
- Thioctic Acid -- pharmacology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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