Interleukin-1 inhibits Leydig cell steroidogenesis primarily by decreasing 17 alpha-hydroxylase/C17-20 lyase cytochrome P450 expression. [electronic resource]
Producer: 19921201Description: 2165-72 p. digitalISSN:- 0013-7227
- 8-Bromo Cyclic Adenosine Monophosphate -- pharmacology
- Animals
- Blotting, Northern
- Cells, Cultured
- Cholesterol Side-Chain Cleavage Enzyme -- analysis
- Gene Expression Regulation, Enzymologic -- genetics
- Interleukin-1 -- pharmacology
- Leydig Cells -- cytology
- Male
- Mice
- Progesterone -- metabolism
- RNA, Messenger -- analysis
- Radioimmunoassay
- Steroid 17-alpha-Hydroxylase -- analysis
- Testosterone -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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