LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. [electronic resource]
Producer: 20031106Description: 415-9 p. digitalISSN:- 1095-9203
- Adaptor Proteins, Signal Transducing
- Clinical Trials as Topic
- Clone Cells -- physiology
- DNA-Binding Proteins -- genetics
- Gene Expression Regulation
- Gene Transfer Techniques
- Genetic Therapy -- adverse effects
- Genetic Vectors
- Hematopoietic Stem Cell Transplantation
- Hematopoietic Stem Cells -- physiology
- Humans
- Infant
- LIM Domain Proteins
- Leukemia-Lymphoma, Adult T-Cell -- etiology
- Metalloproteins -- genetics
- Mutagenesis, Insertional
- Promoter Regions, Genetic
- Proto-Oncogene Mas
- Proto-Oncogene Proteins
- Proto-Oncogenes
- Receptors, Interleukin-2 -- genetics
- Retroviridae -- genetics
- Severe Combined Immunodeficiency -- therapy
- T-Lymphocytes -- physiology
- Transcription, Genetic
- Virus Integration
- Virus Replication
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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