Biphenyl-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme. [electronic resource]
Producer: 20040616Description: 3685-8 p. digitalISSN:- 0960-894X
- 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase -- antagonists & inhibitors
- Acetyltransferases -- antagonists & inhibitors
- Alkylation
- Anti-Bacterial Agents -- pharmacology
- Fatty Acid Synthase, Type II
- Fatty Acid Synthases -- antagonists & inhibitors
- Multienzyme Complexes -- antagonists & inhibitors
- Mycobacterium tuberculosis -- drug effects
- Mycolic Acids -- metabolism
- Recombinant Proteins -- metabolism
- Thiophenes -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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