Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice. [electronic resource]
Producer: 20031204Description: 665-74 p. digitalISSN:- 0161-6412
- 8-Hydroxy-2'-Deoxyguanosine
- Aged
- Aged, 80 and over
- Alzheimer Disease -- metabolism
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Brain -- metabolism
- Cerebral Arteries -- pathology
- Cerebrovascular Disorders -- complications
- DNA, Mitochondrial -- genetics
- Deoxyguanosine -- analogs & derivatives
- Disease Models, Animal
- Electron Transport Complex IV -- metabolism
- Endothelium, Vascular -- metabolism
- Humans
- Immunohistochemistry
- Mice
- Mice, Transgenic
- Microscopy, Electron
- Middle Aged
- Mitochondria -- metabolism
- Neurons -- metabolism
- Oxidative Stress -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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