Inhibition of CD3-linked phospholipase C by phorbol ester and by cAMP is associated with decreased phosphotyrosine and increased phosphoserine contents of PLC-gamma 1. [electronic resource]
Producer: 19920218Description: 1496-501 p. digitalISSN:- 0021-9258
- Antigens, CD -- metabolism
- Antigens, Differentiation, T-Lymphocyte -- metabolism
- CD3 Complex
- Cell Line
- Colforsin -- pharmacology
- Cyclic AMP -- metabolism
- Dose-Response Relationship, Drug
- Humans
- Inositol Phosphates -- metabolism
- Kinetics
- Muromonab-CD3
- Peptide Mapping
- Phosphates -- metabolism
- Phosphopeptides -- isolation & purification
- Phosphoproteins -- isolation & purification
- Phosphorylation
- Phosphoserine -- analysis
- Phosphotyrosine
- Receptors, Antigen, T-Cell -- metabolism
- Tetradecanoylphorbol Acetate -- pharmacology
- Trypsin
- Type C Phospholipases -- antagonists & inhibitors
- Tyrosine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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