A single amino acid substitution is sufficient to modify the mitogenic properties of the epidermal growth factor receptor to resemble that of gp185erbB-2. [electronic resource]
Producer: 19921119Description: 3927-33 p. digitalISSN:- 0261-4189
- 3T3 Cells
- Amino Acid Sequence
- Animals
- Arginine
- Base Sequence
- Codon -- genetics
- DNA Replication -- drug effects
- Epidermal Growth Factor -- metabolism
- ErbB Receptors -- genetics
- Genetic Vectors
- Kinetics
- Mice
- Mitogens
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Oligodeoxyribonucleotides
- Phosphorylation
- Protein-Tyrosine Kinases -- genetics
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogenes
- Receptor, ErbB-2
- Repetitive Sequences, Nucleic Acid
- Signal Transduction
- Threonine
- Thymidine -- metabolism
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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