The treatment of patients with metastatic melanoma and renal cell cancer using in vitro expanded and genetically-engineered (neomycin phosphotransferase) bulk, CD8(+) and/or CD4(+) tumor infiltrating lymphocytes and bulk, CD8(+) and/or CD4(+) peripheral blood leukocytes in combination with recombinant interleukin-2 alone, or with recombinant interleukin-2 and recombinant alpha interferon. [electronic resource]
Producer: 19921020Description: 411-30 p. digitalISSN:- 1043-0342
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- CD4 Antigens
- CD8 Antigens
- Clinical Protocols
- Combined Modality Therapy
- Genetic Engineering
- Genetic Therapy
- Humans
- Immunotherapy, Adoptive
- Interferon Type I -- administration & dosage
- Interleukin-2 -- administration & dosage
- Kanamycin Kinase
- Kidney Neoplasms -- therapy
- Leukocyte Transfusion
- Leukocytes -- immunology
- Lymphocytes, Tumor-Infiltrating -- immunology
- Melanoma -- secondary
- Phosphotransferases -- genetics
- Recombinant Proteins -- administration & dosage
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Publication Type: Journal Article
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