The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases. [electronic resource]
Producer: 19920623Description: 637-41 p. digitalISSN:- 0264-6021
- Base Sequence
- Catalysis
- Cell Membrane -- enzymology
- DNA -- chemistry
- Enzyme Activation
- Gelatinases
- Glycoproteins -- metabolism
- Humans
- Kinetics
- Molecular Sequence Data
- Molecular Weight
- Mutagenesis
- Neoplasm Proteins -- metabolism
- Pepsin A -- chemistry
- Peptide Fragments -- metabolism
- Structure-Activity Relationship
- Tissue Inhibitor of Metalloproteinase-2
- Tissue Inhibitor of Metalloproteinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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