The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors. [electronic resource]
Producer: 19920323Description: 1281-5 p. digitalISSN:- 0027-8424
- Animals
- Arteriosclerosis -- metabolism
- Binding, Competitive
- Fibroblasts -- metabolism
- Humans
- Hydrogen-Ion Concentration
- In Vitro Techniques
- Macaca nemestrina
- Macromolecular Substances
- Mice
- Osteonectin -- metabolism
- Platelet-Derived Growth Factor -- chemistry
- Protein Binding
- Receptors, Cell Surface -- metabolism
- Receptors, Platelet-Derived Growth Factor
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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