Disruption of the cystic fibrosis transmembrane conductance regulator gene in embryonic stem cells by gene targeting. [electronic resource]
Producer: 19930528Description: 177-81 p. digitalISSN:- 0962-8819
- Animals
- Base Sequence
- Blastocyst -- physiology
- Blotting, Southern
- Cloning, Molecular
- Cystic Fibrosis -- genetics
- Cystic Fibrosis Transmembrane Conductance Regulator
- Embryo, Mammalian -- physiology
- Exons
- Female
- Humans
- Hypoxanthine Phosphoribosyltransferase -- genetics
- Membrane Proteins -- genetics
- Mice
- Mice, Transgenic
- Molecular Sequence Data
- Mutagenesis, Insertional
- Oligodeoxyribonucleotides
- Organ Specificity
- Polymerase Chain Reaction -- methods
- Restriction Mapping
- Stem Cells -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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