PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity. [electronic resource]
Producer: 20031103Description: 935-44 p. digitalISSN:- 0021-9738
- Animals
- Blood Glucose -- metabolism
- CCAAT-Enhancer-Binding Proteins -- genetics
- Cells, Cultured
- DNA-Binding Proteins -- genetics
- Gene Expression Regulation
- Hepatocytes -- cytology
- Humans
- Insulin -- metabolism
- Isoenzymes
- Lipid Metabolism
- Liver -- chemistry
- Male
- Mice
- Mice, Knockout
- Phenotype
- Protein Kinase C -- genetics
- Rats
- Sterol Regulatory Element Binding Protein 1
- Tissue Distribution
- Transcription Factors -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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