Neutralization of autocrine transforming growth factor-beta in human cord blood CD34(+)CD38(-)Lin(-) cells promotes stem-cell-factor-mediated erythropoietin-independent early erythroid progenitor development and reduces terminal differentiation. [electronic resource]
Producer: 20040416Description: 557-67 p. digitalISSN:- 1066-5099
- ADP-ribosyl Cyclase -- analysis
- ADP-ribosyl Cyclase 1
- Antigens, CD -- analysis
- Antigens, CD34 -- analysis
- Antigens, Differentiation -- analysis
- Autocrine Communication
- Cell Differentiation
- Cell Lineage
- Erythroid Precursor Cells -- chemistry
- Erythropoiesis
- Erythropoietin -- pharmacology
- Fetal Blood -- cytology
- Hematopoiesis
- Hematopoietic Cell Growth Factors -- drug effects
- Humans
- Kinetics
- Membrane Glycoproteins
- Neutralization Tests
- Stem Cell Factor -- antagonists & inhibitors
- Transforming Growth Factor beta -- antagonists & inhibitors
- Transforming Growth Factor beta1
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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