A novel water-soluble selective CRF1 receptor antagonist, NBI 35965, blunts stress-induced visceral hyperalgesia and colonic motor function in rats. [electronic resource]
Producer: 20031128Description: 32-42 p. digitalISSN:- 0006-8993
- Amphibian Proteins
- Animals
- Autoradiography
- CHO Cells
- Colon -- drug effects
- Cricetinae
- Cyclic AMP -- metabolism
- Defecation -- drug effects
- Dose-Response Relationship, Drug
- Gastrointestinal Transit -- drug effects
- Humans
- Male
- Maternal Deprivation
- Peptide Hormones
- Peptides -- pharmacology
- Rats
- Receptors, Corticotropin-Releasing Hormone -- antagonists & inhibitors
- Stress, Physiological
- Transfection
- Vasodilator Agents -- pharmacology
- Viscera -- drug effects
- Water
- CRF Receptor, Type 1
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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