A bicistronic SIN-lentiviral vector containing G156A MGMT allows selection and metabolic correction of hematopoietic protoporphyric cell lines. [electronic resource]
Producer: 20040507Description: 737-47 p. digitalISSN:- 1099-498X
- Animals
- Antigens, CD34 -- immunology
- Antineoplastic Agents -- pharmacology
- Carmustine -- pharmacology
- Cell Line
- DNA, Complementary -- genetics
- Drug Resistance, Neoplasm
- Ferrochelatase -- genetics
- Gene Expression Regulation
- Gene Expression Regulation, Viral
- Genetic Therapy
- Genetic Vectors
- Green Fluorescent Proteins
- Humans
- Lentivirus -- genetics
- Luminescent Proteins -- genetics
- Mice
- O(6)-Methylguanine-DNA Methyltransferase -- genetics
- Point Mutation
- Porphyria, Hepatoerythropoietic -- genetics
- Promoter Regions, Genetic
- T-Lymphocytes -- immunology
- Time Factors
- Transgenes
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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